![]() ![]() The first release of the annotation of the 44 ENCODE regions was frozen on 29 April 2005 and was used in the first ENCODE Genome Annotation Assessment Project (E-GASP) workshop. It was envisaged that the results of the first two phases will be used to determine the best path forward for analysing the remaining 99% of the human genome in a cost-effective and comprehensive production phase. As part of this stage, the GENCODE consortium was formed to identify and map all protein-coding genes within the ENCODE regions. The pilot stage of the ENCODE project aimed to investigate in great depth, computationally and experimentally, 44 regions totaling 30 Mb of sequence representing approximately 1% of the human genome. The project was designed with three phases - Pilot, Technology development and Production phase. Since September 2009, GENCODE has been the human gene set used by the Ensembl project and each new GENCODE release corresponds to an Ensembl release. The latest release for the mouse geneset annotations is Gencode M25, also with a freeze date December 2020. This release utilises the latest GRCh38 human reference genome assembly. The most recent release of the Human geneset annotations is Gencode 36, with a freeze date of December 2020. GENCODE is currently progressing towards its goals in Phase 2 of the project. 9.2 lncRNA Expression Microarray Design.The result will be a set of annotations including all protein-coding loci with alternatively transcribed variants, non-coding loci with transcript evidence, and pseudogenes. Given the initial success of the project, GENCODE now aims to build an “Encyclopedia of genes and genes variants”. ![]() The GENCODE consortium was initially formed as part of the pilot phase of the ENCODE project to identify and map all protein-coding genes within the ENCODE regions (approx. GENCODE is a scientific project in genome research and part of the ENCODE (ENCyclopedia Of DNA Elements) scale-up project. All gene features in Human & mouse genome ![]()
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